0000001453 00000 n L ̇��?�֠˰=?A�)�[����!s������f`��c 6�D � kb The Duplex system helps pharmacies comply with JCAHO and USP Chapter <797> by offering a “most ready-to-use form” for drug delivery. 0000001956 00000 n Pricing & Availability *Call for pricing and availability. 0000013312 00000 n For Duplex users, Albert says, “I think the most important thing is patient safety. 0000016737 00000 n 0000002105 00000 n Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. 65 34 Pease Place, Suite 102. 0000016041 00000 n The DUPLEX presentation comprises 50ml dextrose 5% injection in one compartment and the drug powder in a separate compartment. Surgery should be expected to last no longer than 3 hours. B Braun’s Duplex Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. DUPLEX® Drug Delivery System Directions for Use Removal from Multi-Pack Tray . 0000004989 00000 n 0000105147 00000 n When the delivery efficiency was more quantitatively analyzed by flow cytometry, 88% of the cells treated with L-ds showed internalization of the L-DNA duplex (Fig. 0000134022 00000 n Duplex drug delivery system containing cefazolin and dextrose injection in separate chambers 117 and the commercially available premixed cefazolin injection (frozen) should be used only for IV infusion. �[����8�����5�߰�]c%&�p�A 1. 1935 J.N. 0000002229 00000 n 0000005078 00000 n xref The DUPLEX Drug Delivery System is a closed system that ensures sterility and dose accuracy. Since the conceptualization of the “magic bullet”, i.e. Remove top tray. trailer <]>> startxref 0 %%EOF 13 0 obj<>stream DUPLEX Drug Delivery Cephalosporins Systems Manufacturer: B Braun Medical Inc. Two-compartment flexible IV container stores premeasured drug and diluent doses separately until administration without thawing or mixing procedures Easy-to-use, convenient and suitable for bedside use Duplex® is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the upper chamber and powdered drug in the lower chamber. 0000011036 00000 n 0000148670 00000 n The DNA duplex functions as a doxorubicin carrier through intercalation, and cetuximab serves as the targeting agent. 0000001850 00000 n DUPLEX® DRUG DELIVERY SYSTEM ©2005 B. Braun Medical Inc. Over a 0.15 to 3 g dose range in healthy adult subjects, the values of elimination half-life ranged from 5.8 to 8.7 hours; apparent volume of distribution from 5.78 to 13.5 L; plasma clearance from 0.58 to 1.45 L/hour; and renal clearance from 0.32 to 0.73 L/hour. The delivery system showed significant selectivity and anticancer potential towards EGFR + cancer cells. The DUPLEX two-compartment flexible IV container stores pre-measured drug and diluent … 0000007171 00000 n 0000007787 00000 n startxref x�b```f``�c`e`��� �� @16� "��-�XKd_200~�+��0{�-�1��&�C��Z��d��K&m�K�wy�h�x�{��䐞�ͪM�\g-8�Ul�a�^=�U��"�d.��l�Nʚn��� �`�д���%J`��KG��l� 0000006220 00000 n 0000002020 00000 n The caregiver simply squeezes the bag to mix the drug and diluent just prior to administration. The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. Y36-002-415 DUPLEX ™ Package Insert DRUG DELIVERY SYSTEM CEFAZOLIN FOR INJECTION USP and Dextrose Injection USP DESCRIPTION Cefazolin for Injection USP and Dextrose Injection USP is a sterile, nonpyrogenic, single use, packaged combination of Cefazolin Sodium USP (lyophilized) and sterile iso-osmotic diluent in the DUPLEX sterile container. 0000013098 00000 n It is conveniently activated at point of care, and administered with the right dose and at the right time. endstream endobj 66 0 obj<> endobj 68 0 obj<>/Font<>>>/DA(/Helv 0 Tf 0 g )>> endobj 69 0 obj<> endobj 70 0 obj<>/Font<>/XObject<>/ProcSet[/PDF/Text/ImageB]/ExtGState<>>> endobj 71 0 obj<> endobj 72 0 obj<> endobj 73 0 obj<> endobj 74 0 obj[/CalRGB<>] endobj 75 0 obj<> endobj 76 0 obj<> endobj 77 0 obj<> endobj 78 0 obj<> endobj 79 0 obj<>stream B BRAUN 3175-11 DUPLEX DRUG DELIVERY SYSTEM Please See More Product Details Below B-BRAUN-3175-11 B Braun Medical - 2g Cefotetan For Injection USP & Dextrose Injection, 50mL (Rx), 24/cs (For Healthcare Professionals Only). The purpose of this study is to demonstrate the safety and pharmacokinetics of Cefazolin 2g for Injection USP and Dextrose Injection USP in the DUPLEX® Drug Delivery System to Cefazolin 1.5g for Injection USP and Dextrose Injection USP in daily doses of 6g in healthy adult subjects for … 0000004814 00000 n %PDF-1.4 %���� The Duplex system arrives at the hospital pre-filled with the proper doses of drug and diluent. The gold-award DUPLEX system is easy to use; just break the quick-release seal and squeeze to mix drug and diluent prior to administration. %PDF-1.3 %���� q����$a�{垝}0�x endstream endobj 11 0 obj<. 0000055766 00000 n DUPLEX Drug Delivery Systems-Cephalosporins by B Braun Medical Two-compartment flexible IV container stores premeasured drug and diluent doses separately until administration without thawing or mixing procedures Easy-to-use, convenient and suitable for bedside use Pharmaceuticals and diluents are mixed just prior to administration 119 For solution and drug compatibility information, see Compatibility under Stability Duplex is easy to stock as it can be stored at room temperature, with 18-month minimum dating, and fits in automated medication dispensing systems. 0000148634 00000 n DUPLEX ® is easy to stock as it can be stored at room temperature, with 18-month minimum dating, and fits in automated medication dispensing systems. Cefoxitin powder for solution for injection, BBraun, 1 gram, 50 mL DUPLEX Drug Delivery System, 24 count, NDC 00264-3123-11 Estimated Resupply Dates Hikma has cefoxitin 10 gram vials on allocation. 0000050912 00000 n ����3����6M�-P�T/�}���6�F�]2/�� 0000008605 00000 n Ready-to-Use Drug Delivery System Cephalosporins in … Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body some time based on nanoparticles as needed to safely achieve its desired therapeutic effect. 0000067397 00000 n 0000015044 00000 n The practice of drug delivery has changed dramatically in the past few decades and even greater changes are … 0000119149 00000 n Add to Cart. 10 0 obj <> endobj xref 10 40 0000000016 00000 n 0000016270 00000 n 0000014191 00000 n 67 0 obj<>stream 0000012197 00000 n <<1e776483c6fdb649a1ce47ff29a83ed0>]>> DUPLEX Drug Delivery Systems-Cephalosporins by B Braun Medical. 0000014972 00000 n The DUPLEX Drug Delivery System two-compartment flexible IV container stores pre-measured and diluent doses separately until administration. 0000133986 00000 n 0000003412 00000 n 0000000976 00000 n 0000119374 00000 n �B�M�JP@����B�g�V��C��V~�K��M������hg�wjg~�~��E 0000002595 00000 n 0000119225 00000 n %%EOF The SmartDose platform offers a wearable, subcutaneous injector with an integrated drug delivery system that incorporates human factors and usability testing to deliver a truly patient-centric approach to self-administration. It is conveniently activated at point of care, and administered with the right dose and at the right time. 0000043775 00000 n B. Braun Medical announced that 1g and 2g cefepime for injection and dextrose for injection are available in B. Braun’s DUPLEX Drug Delivery System. 0000017286 00000 n 0000001458 00000 n 65 0 obj <> endobj 0000023227 00000 n 0000002139 00000 n 0000010528 00000 n 0000005535 00000 n -- Tall man labeling helps to differentiate the drugs in the Duplex Drug Delivery System The DUPLEX® System consists of a pre-filled, PVC-free, DEHP-free, and latex-free IV bag containing proper doses of drug and diluent in different compartments separated by a quick release seal. 0000172528 00000 n 0000001322 00000 n Drugs have long been used to improve health and extend lives. Duplex drug-delivery pouch A twin-compartment package that mixes a drug in one section with a diluent in the other–only when the user activates them–nabbed a gold award for B. Braun Medical's Duplex® drug-delivery system (N). 0000001756 00000 n 0000014879 00000 n The Duplex system consists of a pre-filled, PVC-free, DEHP-free, and latex-free IV bag containing proper doses of drug and diluent in different compartments separated by a quick release seal. Patient Labeling and Drug Powder/Diluent Inspection 0000018601 00000 n 0000001375 00000 n 0000009832 00000 n 0000044157 00000 n Duplex ® is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the upper chamber and powdered drug in the lower chamber. 0000035447 00000 n DUPLEX® Drug Delivery System: Instructions for Use - YouTube The Duplex® Drug-Delivery System Additional information Available in CEFOXITIN (as Sodium) 1g Powder for injection ( IV) and CEFTRIAXONE (as Sodium) 1g Powder for injection (IV) B. Braun Medical Inc. recently announced it received US FDA approval for 2-g Cefazolin for Injection USP and Dextrose Injection USP in B. Braun’s DUPLEX Drug Delivery System. The product (diluent and drug) contact layer is a mixture of thermoplastic rubber and a polypropylene ethylene copolymer that contains no plasticisers. 0000001096 00000 n trailer 0000020559 00000 n Tear tape strips from one or both sides of the trays. ��V��ճ�>+˃�u��ȃ��\� 0000002436 00000 n H��Vms�6����t�c�~lI��M{��\;�aPj[�2ȯ�J��9�\n Quantity. 0000001577 00000 n This is a multiple-center, open-label, PK study of cefazolin in children aged 10 to 12 years (inclusive) receiving 1g or 2 g of cefazolin delivered via the DUPLEX® drug delivery system for surgical prophylaxis. 0000030731 00000 n The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. 0000119299 00000 n 0000035980 00000 n To avoid inadvertent activation, DUPLEX Container should remain in the folded position until activation is intended. 2b).After we found that L-ds can be internalized into cells, we next attempted to deliver Dox into the cells by employing L-ds as the drug … 0000012335 00000 n !�,T�QHII��k@v4PB���}#��bS�R>F5��҇���,�rq����j�-$�g���2�=L�^�1��8mYv��1�S� 0000050336 00000 n Ceftriaxone 0000009825 00000 n You can always be prepared for surgical cases that require preop administration of 2-gram Cefazolin with B. Braun's newly approved 2 gram Cefazolin DUPLEX Drug Delivery System. 0 0000001551 00000 n 0000001672 00000 n 0000015326 00000 n DUPLEX… 0000028978 00000 n DUPLEX … 0000000016 00000 n 0000006974 00000 n Because no pharmacy-based compounding is required, the possibility of compounding calculation errors is eliminated. Introduction. It consists of a prefilled, latex- and PVC/DEHP-free IV bag containing accurate doses of drug and diluent in different compartments, separated by a quick release seal. $0.00 Price. ��]Xs�_���У@����/P�c� ��_R���. 0000029495 00000 n With the Duplex system, there is no possibility of delivering the diluent without the drug.” The Duplex system contains no plasticizers, is latex-free, and PVC-free, increasing safety for patients and the environment. 0000044367 00000 n The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. 0000004227 00000 n 0000004086 00000 n Functions as a doxorubicin carrier through intercalation, and administered with the right dose at! Is eliminated no longer than 3 hours container stores pre-measured pharmaceuticals and diluent doses container should remain in upper. 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